Lyme disease, a mysterious tick-borne illness, is the fastest spreading vector-borne disease. Over the past decade, rising temperatures have encouraged the ticks to migrate at an alarming speed into Canada and other new territories around the world. Ticked Off: The Mystery of Lyme Disease is a fascinating and eye-opening documentary that explores a disease that has devastating effects, is often misdiagnosed and mistreated, and continues to be mired in a medical controversy.