The quality of healthcare and sanitation varies significantly around the world. Despite improvements in quality of life and education over the past decades, there is still much work to be done regarding the access to healthcare and sanitation services and awareness of public health issues. To fight against disease and avoidable health issues, efforts should be directed towards prevention and education. Featured ARCHITECTS OF CHANGE: 1. Garth Japhet (Doctor and President of Heartlines, South Africa) achieving positive social change by promoting lived values, strong relationships and civic action in southern Africa. 2. Jack Sim (Founder of the World Toilet Organization, Singapore) a global non-profit committed to improving toilet and sanitation conditions worldwide. 3. Dr. Perumalsamy Namperumalsamy (Founder of the Aravind Eye Hospital, India) eradicating cataract related blindness in India.